Where to Find Help with Research Papers

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Classroom Is Not The Classroom Of Yesterday - 1050 Words

The classroom of today is not the classroom of yesterday. We are accountable so much more to the learning needs of our students. The use of technology in the classroom is changing the way in which we teach our students. We have a responsibility to prepare students for the demands of an ever-changing world, through facilitating learning in a technology rich environment, where students and teachers don’t just learn about technology, they use it to achieve powerful learning and teaching and improve student learning outcomes. The challenge is to create engaging, supportive learning environments and opportunities that stimulate, extend and deepen student learning. These environments should incorporate seamless use of technologies students use†¦show more content†¦Within the United States, Partnerships for 21st century learning developed an education framework with teachers, educational and business leaders that provides a list of skills students need to succeed in work, l ife and social community. The framework sees the core subjects of reading, writing, and numeracy supported by learning and innovation skills (critical thinking, communication, collaboration, and creativity). Furthermore, the 21st century learner would see further life and career skills, information, media and technology skills integrated across the core subject matters. Partnerships for 21st Century Learning notes that â€Å"the research tell us about which competencies are most clearly associated with positive outcomes for individuals in many spheres of life, including educational attainment, transitions to postsecondary education and training, employment, and health and well-being.† The Ontario government (2016) in the document â€Å"Towards Defining 21st Century Competencies† notes that â€Å"The primary goal of the province’s education system is to enable students to develop the knowledge, skills, and characteristics that will lead them to become personally successful, economically productive, and actively engaged citizens.† They assert that key 21st century competencies (critical thinking, communication, collaboration, creativity and innovation) have measurable benefits for multiple areas of lifeShow MoreRelatedA Dual Immersion Program For Hispanic Children From Kindergarten From Barbour Dual Language Immersion Academy1010 Words   |  5 Pagesfieldwork assignments, I have not met another teacher who has been so ahead of her peers in evolving the classroom for successful, 21st century education. Barbour runs a dual immersion program for Latino children from kindergarten through eighth grade. Starting in the lower grades more Spanish instruction is the main concentration with English incorporated more and more each year. The classrooms are split as evenly as possible with English speakers and Spanish speakers of all backgrounds and ethnicitiesRead MoreDifferentiated Curriculum Is Absolutely Necessary Essay1156 Words   |  5 PagesDifferentiated Curriculum To be the best, is constantly changing. What was the best yesterday is not the best today, therefore one must possess a growth mindset. Tomlinson and Allan (2000) stated whatever does not change does not grow, and whatever does not grow atrophies. Many schools and classroom are atrophying because there is a lack of a growth mindset. There is compelling knowledge developed in recent generations on how students learn, including gender, starting point of readiness, cultureRead MoreThe Relationship Between Educator And Student929 Words   |  4 Pagesdistinct archetypes of teacher often stick out to the public eye: the Mrs. Sullivan, the Mr. Stacy, and the Mr. Smith. Shining black dress shoes trot their way down the tiled hallway as Mrs. Sullivan calmly makes her way to her pristine white walled classroom. She follows her routine every morning, making it to her class exactly fifteen minutes before the bell rings, just enough time to prepare for her pupils. This woman has taught class after class for years. Respected, radiating intelligence from everyRead MoreA Report On The Classroom1335 Words   |  6 PagesJournal Day 7 No students for the seminar in the classroom which made the room feel weird this morning. However, it is hard to really be able to talk sometime with the teacher because students are in the classroom, or stopping by pretty much all the time. We are planning to sit down and make up my schedule for the classes, and we agreed to do the honors classes last since it is the college course and extremely fast paced. He is going to try to get the IEPs to me, but students keep coming in andRead MoreDaniel Inners : An Inspiring Sixth Grade Teacher At Spring Grove Intermediate School887 Words   |  4 Pagesif it is for his students. One of the greatest feeling he said was being able to encourage and help the not so smart kid because he says he was that kid when he was in school and his teachers told him he wouldn’t go anywhere. When asked if his classroom is set up a certain way he responds the on the first day no. The kids are allowed to sit where ever they want. This allows him to see who is friends with who and separates them if needed. He changes their seats every month because the students getRead MoreThe Role Of Educational Technology And The Philosophy Of Education918 Words   |  4 Pagesbelieve a good education can secure a better future. Furthermore, education is the best investment in the future, and in today’s world, the role of education has become even more vital. At the outset, John Dewey said, â€Å"If we teach today as we taught yesterday, we rob our children of tomorrow.† (2008). It means teaching today is very different compares to twenty years ago. Today’ s generation are immersed in media. Our world is constantly being influenced by technology and I believe it is important toRead MorePersonal Leadership For The Fall Of 2015855 Words   |  4 Pageswith honors and within a month of graduation I received my first teaching position as a second grade teacher. Moreover, I still remember that second grade class as if it were yesterday that class fondly. I remember walking into the class that first day of school after spending a week decorating and organizing my classroom. I thought, â€Å"This is the place I am meant to be†. As a second grade, teacher you play a vital part in students development. You set the standard for their experience of learningRead MoreJob Satisfaction Is Not Just About Job Conditions911 Words   |  4 PagesPearson/Australia, 30/8/2013. VitalBook file. I know the teachers and aids all do this, with the students well. I have wonderit but after our meeting yesterday if the treat each other as well. I think they need to practice prosocial behavior between departments more i.e. aids and teachers specifically based on my limited observation and dialog yesterday from the ladies. Prosocial behaviour is a hallmark of social competence in children of all ages. However, it is clear that the developmental andRead MoreThe Teacher I Will Interview954 Words   |  4 Pageswith a resource teacher. Currently, she has a total of twenty-four students in her class with eight students being service on an Individual Education Plan. I was able to interview Ms. McFadden in person as she suggests I come to observed her classroom. Her request is a total surprise to me, I did not realize that her school operate on the year round model. We arranged to meet right away in the morning so that I could meet and interact with her students. Ms. McFadden is quite experienced and quickRead MoreHow Do People Learn (Language)?829 Words   |  4 Pages†¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   cat †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   He has a cat. †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   She †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   She has a cat. †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   pencil †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   She has a pencil. TYPICAL CLASSROOM FEEDBACK Today most educators reject this strict form of Behaviorist learning theory (and ALM is rarely used).   Nevertheless, we can see examples of this way of thinking in almost every language classroom around the world.   Let’s look at a typical bit of â€Å"teacher-learner† interaction: †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   01   T:   What time is it? †¢Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   02   S:   Half

Oedipus the King Fate vs. Free Will Essay examples

Sophocles’ Oedipus the King: Fate vs. Free Will In Oedipus the King, one of Sophocles’ most popular plays, Sophocles clearly depicts the Greek’s popular belief that fate will control a man’s life despite of man’s free will. Man was free to choose and was ultimately held responsible for his own actions. Throughout Oedipus the King, the concept of fate and free will plays an integral part in Oedipus destruction. Destined to marry his mother and murder his father, Oedipus was partly guided by fate. This prophecy, as warned by the Oracle of Apollo at Delphi, was absolute and would inevitably come to pass. As for free will, Oedipus’ actions, temper, impulsive nature and pride (hubris) as well as his erroneous judgment (hamartia) all†¦show more content†¦Not knowing he was the murderer, Oedipus had now cursed himself. Whoever he is, a lone man unknown in his crime or one among many, let that man drag out his life in agony, step by painful step – I curse myself as well†¦ if by any chance he proves to be an intimate of our house, here at my hearth, with my full knowledge, may the curse I just called down on him strike me! (606) Oedipus journey in search of Laius’ murderer has merely helped the prophecy become reality. His ignorance, pride and remorseless quest for the truth ultimately contributed to his destruction. An explicit example can be seen when Oedipus was told (after threatening Tiresias), that he was responsible for Laius’ murder. Oedipus became enraged and called the blind prophet a liar. Oedipus thought he could overcome the gods, but in fact, his every action moved him closer to his destiny. Upon unearthing of the truth of his birth from the shepherd, Oedipus cries out, â€Å"O god all come true, all burst to light! O light now let me look my last on you! I stand revealed at last cursed in my birth, cursed in marriage, cursed in the lives I cut down with these hands†. (631). Oedipus now knew that his fate had indeed come to pass, and feels cursed by it. Due to the crimes he committed, Oedipus punishes himself (free will) by stabbing his eyes with one of Jocasta’s brooches. Overall, Oedipus achieves his foremost sin when he attempts toShow MoreRelatedOedipus the King: Fate Vs Free Will Essay639 Words   |  3 Pages Oedipus the King, was written by Sophocles between C.A.496-406B.C. In this play, Oedipus is a great example of Sophocles’ belief that fate will control a man’s life no matter how much free will exists. Oedipus is a man of unflagging determination and perseverance, but one who must learn through the working out of a terrible prophecy that there are forces beyond any man’s conceptualization or control. Oedipus’ actions were determined before his birth, yet Oedipus’ actions are entirely determinedRead MoreThe Value Of Leadership In Oedipus Rex By Sophocles1326 Words   |  6 PagesBased on evidence, Athenians valued bravery, confidence and heroic strength in their leaders. For example, the entire reason Oedipus from Oedipus Rex by Sophocles became king of Thebes is because he defeated the Sphinx that was guarding the city, saving the citizens (info from the backstory). On page 11, a senator makes the comment, â€Å"if his bosom holds a grain of fear, curses like yours he never will abide.† The reader can assume the Athenians valued bravery because the senator makes a comment againstRead MoreFate vs Free Will1663 Words   |  7 PagesOedipus The King: Fate Vs. Free Will The ancient Greek writer, Sophocles suggests that while there are factors beyond mankind’s control that we have the power to make choices that affect our destiny. In his play, Oedipus the King, Sophocles makes it quite clear that although everyone is born with a fate, you have the ability to alter its direction and toll. The main character of the play, Oedipus, is based on the way Sophocles portrays the equilibrium between fate and freewill, and shows theRead MoreWhat Does Oedipus the King Show Us About Greek Thought on Fate, Gods, and Free Will?1321 Words   |  5 PagesWhat does Oedipus the King show us about Greek thought on Fate, the gods, and free will? Oedipus is a play that explores the styles of freewill and fate throughout its totality. This is the tale of a guy and how he tries to resist his own fate and thus focuses on his defense of the future that he needs. Oedipus wished to reject his personal predestination and wanted make a life of his own choosing. The tale all started by a prediction upon Oedipus life that therw will come a day when he wouldRead MoreAn Analysis of Fate vs. Free Will in the Theban Plays1392 Words   |  6 PagesAn Analysis of Fate vs. Free Will in the Theban Plays When Teiresias asks in Antigone (line 1051), What prize outweighs the priceless worth of prudence? he strikes (as usual) to the heart of the matter in Sophocles Theban Plays. Sophocles dramatizes the struggle between fate and free will, in one sense, but in another sense the drama might be better understood as the struggle between the will of the goods (which it is prudent to follow, according to Teiresias) and mans will (which is oftenRead MoreEssay about Fate vs. Free Will (Oedipus Rex)607 Words   |  3 PagesFate vs. Free Will Sophocles creates a world that makes the reader think about the complex and mysterious battle between fate and free will in his play Oedipus The King. To the characters, fate is real and that’s what they believe in. The audience sees that Oedipus is the one making the divisions and altimetry it is himself that leads to his downfall. Apollo, the Greek god of prophecy, intellectual pursuits and pelage, told Oedipus about his tragic future. When we first encounter OedipusRead MoreOedipus Fate And Fate Essay777 Words   |  4 PagesFate as defined by the Merriam Webster dictionary is ‘an inevitable and often adverse outcome, condition, or end’. Sophocles discusses fate vs free will in his plays. In the play Oedipus Rex there was a prophecy that Oedipus was destined to kill his father and marry his mother, he attempts to escape his destiny by running away to Thebes where he meets his fate. In the play Antigone, that main character Antigone decides to go against Creon’s (her uncle who has inherited the throne) decree and buryRead MoreWilliam Shakespeare s Oedipus The King 909 Words   |  4 PagesEnglish Assignment – Oedipus The King In the story, Oedipus The King, written by Sophocles, two important aspects of Oedipus’ character that lead to his demise are his determination to find the truth of his origin, as well as his anger. These are flaws that negatively affect the tragic outcome at the end of the plot. Oedipus first shows signs of anger when he does not want to hear what Tiresias has to say about the murderer of Laius, even after the ruler begs for the truth. Oedipus yells, Enough! IRead MoreCan You Truly Ever Escape?2156 Words   |  9 PagesThe most memorable of his warnings was in Sophocles’ Oedipus the King, king of Thebes that he was the land’s pollution. The prophet Tiresias spoke the truth about Oedipus—â€Å"God within reckon that out, and if you find me mistaken, say I have no skill in prophecy†Ã¢â‚¬â€denouncing the tragedy, as the angry Oedipus begins his painful search for the truth about himself. However, the prophecy is Oedipus’s ultimate demise. Oed ipus fought the limits of free will by ignoring social ques, and even disbelieving respectedRead MoreOedipus the King by Sophocles Essay example615 Words   |  3 PagesIn the story of â€Å"Oedipus the King† by Sophocles portrays theme, symbolism, and imagery. With these in mind, they had influence the character to do a few things we wouldn’t normally be doing in today’s society. By showing us the way he acts leads us to knowing the difference between what is right and wrong. Back in the day, we never knew what was shown as being truthful unless someone told you. So not realizing the importance role Oedipus plays is has a significant impact on the audience’s reactions

Experiment Design for Behavioural Brain Research-myassignmenthelp

Question: Discuss about theExperiment Design for Behavioural Brain Research. Answer: Involvement of the Basal Ganglia Domains (Limbic, Associative and Sensorimotor) In Induced Dyskinesia Introduction The management of Parkinsons illness people with a dopamine precursor like the L-dopa boosts the growth of severe changes in motor response as well as involuntary movements referred to as L-dopa induced dyskinesia, a serious complication of L-dopa therapy associated with Parkinsons ailment. The true nature of such manifestations can result to experiments concerning the abnormalities of neural function especially in the corticobasal ganglia motor circuit. However, since the modern theory regarding the arrangement of basal ganglia pathways suggests that both the basal ganglia plus the frontal cortex are put in segregated circuits that are parallel, there is a tremendous proof showing the consistence for associative, limbic and sensorimotor domains (Le Jeune et al., 2008). Ideally, research shows that the motor components of a sub thalamic nucleus as well as the dorso lateral tip have a usual terminal activity at the chorea which is of signifance in dystonia. On the other hand, the metabolic activity of the limbic and associative sub thalamic nucleus is impaired in both scenarios. However, the result initially showed that there exists a pathophysiological disparity between dystonia and the L-dopa induced chorea. According to Le Jeune et al., (2008), it can now be hypothesized that can also reflect the association of opposite pathways in a lopa induced dyskinesia hence increasing the likelihood that it as well relates to the unusual processing of the either associative or limbic information. Hence the rationale of this paper is to design an experiment that identifies if or not the modulation of a loop in the basal ganglia can alter the output in other loops in the systematic fashion. The write up also looks at the changes in the 2DG accumulation in associative, sensorimotor plus the limbic domains of the basal ganglia and thalamic nuclei of groups that are not primate. Materials and Methods Used In the Experiment Nineteen female monkeys were put in separate primate rooms under controlled conditions of light, temperature and humidity. Both food as well as water was provided and animal care was being ensured by a registered veterinarian. The experiment was conducted in respect to the European communitys council directive of September for proper care of laboratory animals. For the experiment protocol, the demographic property showed that every methyl phenyl treated animals monkeys showed a comparable phase of lesion as well as different behaviours. Both the control plus the methyl phenyl treated animals corresponds to those animals in the D25 and D0 groups while dsykinetic plus the nondyskinetic species originated from a population of those animals validated earlier. For the later animals, they were created administration of L-dopa twice a day for up to eight months at a modified dose made to give complete reversal of Parkinsons condition. The animals that contracted serious and reproducible dyskinesia were five while four did not. Regarding the behavioural evaluation, the parkinsonian condition was determined on an animal rating scale using video tape recordings of the animals. After the evaluated a score of zero represented a normal monkey while the score of six and above represented the parkinsonian animal. However, the degree of dyskinesia was measured by use of a dyskinesia disability scale abbreviated as DDS. Zero meant dyskinesia was absent; one meant the condition was mild with rare dyskinetic movements as well as postures. A scale of two mean moderate with outstanding unusual movements and not interfering greatly with the usual behaviour. Three marked regular and sometimes continuous dyskinesia entering via the normal repertoire of activity. A scale of four represented severe continuous dyskinetic activity rendering the animal disabled as well as replacing the actual behaviour (Kirch et al., 2013). 2-DG Procedure During the event the monkeys were killed, they were injected with 2DG deoxy glucose which was sterile saline. After almost one hour, all the monkeys were killed by a pentobarbital overdose , while the L-dopa treated monkeys got their modified dose of L-dopa a quarter an hour prior to the introduction of 2DG. Their brains were removed and stored in a chemical substance to freeze. The inner tissues were cut into pieces of 20 micrometres where they were thaw mounted onto slides containing gelatine substance. After they were freeze dried, the auto radiographic methyl methacrylate standards plus the serial sections were put to hpyerfilm for sixty days at a temperature of 30 degrees Celsius. After two months, densitometry analysis of autoradiograph was done by means of an image analysis method. Each animal was analysed according to four sections per nucleus by an examiner in respect to the radioactivity levels found in contrast with the standards. Later on, the SEM plus the mean bound radi oactivity were subsequently found for every group. Statistical analysis For different comparisons of information, a one-way ANOVA table was employed to check for the general significance followed by a t test for different comparisons. For the behavioural assessment of different comparisons, the kruskal Wallis non parametric test was employed to test the entire significance followed by a t test corrected by different comparisons via Dunns technique. The data were normally distributed plus the significance level of the t test attuned for inequality of measures dispersion like variance if appropriate. Lastly, the analysis was completed using a strata program where a p 0.05 was taken to be significant. Results The 2 deoxy glucose uptake was measured with associative, limbic plus sensorimotor domains of basal ganglia as well as in other target groups of such domains. In that aspect, the outer part of the globus pallidus was classified into three territories namely the associative, sensorimotor and limbic as mentioned earlier. The sub thalamic nucleus was split into associative-limbic and sensorimotor domains. The accumulation of the 2DG was calculated as a whole in the inner parts of globus pallidus as well as in the substantial migra reticulate. There are two outputs of the ganglia due to the continuous overlap between the domains in the nuclei. Ideally, three nuclei were observed in the thalamus. Both the ventral lateral nuclei plus the ventral anterior are known to be thalamic targets of motor loop. The ventral anterior was measured on tiny sections of four millimetres anterior to the anterior commisura where the sub thalamic nucleus is absent and the central lateral was measured accordi ng to sections of six millimetres to anterior commisura where the sub thalamic nucleus is present. However, a mediodorsal nucleus is referred to as the thalamic output of the associative loop of the BG commonly known as basal ganglia. However, the nucleus of the terminus of the stria was considered to be the limbic output of the basal ganglia. Advantages of the Designed Experiment The experiment design is simple and can be applied in different disciplines. The research designs are repeatable hence results can be rechecked as well as verified. The researcher can tailor the experiment as well as maintain validity of the design Limitations of the Experiment Design It was not possible to control the extraneous variable The results obtained in the experiment may not be generalised to a larger population. The reaction of the test subjects cannot be true indicators. Human errors can also play a key role in validity of the subjects. The reaction of the test subjects cannot be true indicators of behaviour in non-experimental environments. In the whole domains of the globus pallidus, 2 deoxy glucose was relatively higher in parkisonian monkeys than the normal monkeys. Both the dyskinetic as well as nondsykinetic animals showed normalised levels of 2 deoxy glucose accumulation in the globus pallidus sensorimotor and limbic. Also, those dyskinetic showed a reduced 2 deoxy glucose uptake in the globus pallidus associative contrary to the methyl phenyl treated as well as non dsykinetic organisms. The 2 deoxy glucose in the two domains were defined in the ST nucleus. Those animals treated with methyl phenyl showed a tremendous decline in 2 deoxy glucose accumulation in the limbic and sensiromotor domains. However, the L- dopa treatments led to a raise in the 2 deoxy glucose levels in the nondsykinetic as well as the nondsykinetic groups. Also, there was no significance group noted within the control groups. The afore mentioned results shows that while nondsykinetic animals presented normalised metabolic activity compared to the control groups dsykinetic organism were distinguished by a tremendous shifts in the 2 deoxy glucose accumulation in associative plus limbic linked structures but not by sensorimotor nuclei (Kirch et al., 2013). The results were obtained from all the animals and those that had died half an hour following L-dopa administration. During this period the D5 parkinsonian symptoms were developed and none of the LID was noted. Instead, LID erupted in the 45th minute onwards in the dsykinetic group and since data obtained from one group is not enough for statistical analysis, a qualitative analysis would provide more insights. Following half an hour after dopamine was administered, 2 deoxy glucose levels in motor nuclei were similar to the nondsykinetic and dsykinetic organisms at an hour after L-dopa was administered. Discussion The primary finding of this experiment is that neural mechanism accountable for LID expressions may too involve associative plus limbic domains but not the sensorimotor domain. Besides, qualitative temporal analysis supports such aspect since in the dsykinetic organism killed when parkiansonian motor abnormalities were developed and prior to the appearance of LID (Kravitz et al., 2010). Therefore, it can be argued that dsykinesia is associated with the pathological metabolic movement in the associative limbic nuclei. The later should not be considered as a movement disorder but also as entailing motivational , affective as well as cognitive aspects of an individual behaviour which been investigated partially in the clinic. The pattern of changes of 2 deoxyglucose accumulation in this experiment matches the original findings from other scholars. For instance, it can be conformed the differential metabolic activity between the components of the ST nucleus and the dorso lateral tip in dsykinetic and nondsykinetic organisms (Sebastianutto et al., 2017). Also, the metabolic activity of basal ganglia motor related structure was not affected in any way in the dsykinetic organism compared to the nondsykinetic. However increased 2 deoxy glucose intake in the GPI must conform to the increased GABAergic tone emanating from the striatum and also from the GPe. According to Kravitz et al., (2010), the reduced 2 deoxy glucose accumulation in the MD of dsykinetic organisms would therefore be the signature impairment of the whole circuit. Since the present study only presents a contaminant variation, it does not at any given moment create a causative connection that remains to be demonstrated directly. Since basal ganglia pathways are considered to be arranged parallel in segregated circuits there is proof showing the continuous funnelling information between the limbic, associative and sensorimotor domains. The same concept was further developed by different scholars by postulating that the same information is continuously by diverse functional domains of basal ganglia via the certain pathways of functional interaction via the basal ganglia circuits. This hypothesis has received lots of accolade from the demonstration that cocaine self-administration produces a continuous involvement sensorimotor, limbic and associative domains. However, chronic L-dopa treatment as well as cocaine administration lead to raised dopamine levels within the striatum can lead to continuous dissemination of information rather than focused processing (Kirch et al., 2013). However, in this write up evidence for comparable mechanisms is being provided but not in the same order that is sensorimotor, followe d by limbic land lastly is associative domain. Together with clinical observations reporting reward deficiency syndrome or the learning deficits in the L-dopa treated persons, it can be postulated that dsykinesia needs no to be seen as a movement disorder, but also as a motivational, affective as well as cognitive disorder. Since the qualitative temporary analysis shows that causative duty of involvement of limbic plus associative nuclei and the direct electrophysiological are mandatory when it comes to the establishment of casual; relationships. Ideally, a shift in the 2 deoxy glucose uptake does not show alteration in firing activity of neurons but shows the integration of shifts during the 45th minute in the entire phase of intrinsic synaptic activity. Moreover, a significant result of this experiment is that LID cannot be continued to being analysed via investigating the motor areas thus rendering unreliable each and every other study that does not pay close attention to the functional organisation of the ganglia loops (Le Je une et al., 2008). Viewing LID is caused as a result of unwanted involvement of limbic as well as associative aspects or as having the or by having limbic and cognitive abnormalities counterparts of LID as is regularly reported by the hyperkinetic complications. For example, say the electrophysiological investigations conforms to the causative hypothesis , modulating the activity of non-motor areas would drastically lower severity of LID , hence offering new drug targets for treatment of the same condition. References Le Jeune, F., Peron, J., Biseul, I., Fournier, S., Sauleau, P., Drapier, S., ... Herry, J. Y. (2008). Subthalamic nucleus stimulation affects orbitofrontal cortex in facial emotion recognition: a PET study. Brain, 131(6), 1599-1608. Kirch, R. D., Meyer, P. T., Geisler, S., Braun, F., Gehrig, S., Langen, K. J., ... Dbrssy, M. D. (2013). Early deficits in declarative and procedural memory dependent behavioral function in a transgenic rat model of Huntington's disease. Behavioural brain research, 239, 15-26. Kravitz, A. V., Freeze, B. S., Parker, P. R., Kay, K., Thwin, M. T., Deisseroth, K., Kreitzer, A. C. (2010). Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry. Nature, 466(7306), 622-626. Sebastianutto, I., Cenci, M. A., Fieblinger, T. (2017). Alterations of striatal indirect pathway neurons precede motor deficits in two mouse models of Huntington's disease. Neurobiology of Disease.